In recent years there has been a  growing interest in calf reshaping alongside high-definition liposuction and fat grafting. However, research on calf fat grafting remains limited, particularly regarding safety and long-term outcomes.  This paper reviews the most advanced and recently published literature on this topic, combining current scientific findings with practical surgical insights, to provide a comprehensive guide for optimizing outcomes while ensuring the highest standards of patient safety in fat grafting to the calf.